Truths and myths about tryptophan — and why it's so healthy for you
Truths and myths about tryptophan — and why it's so healthy for you
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Most people think tryptophan leads to serotonin, calmness, or sleepiness. But for some people, it takes a very different, and potentially dangerous, biochemical path. Dr. J explains how certain genetic variants in the TPH2 enzyme can divert tryptophan toward the kynurenine–quinolinic acid pathway. Quinolinic acid is neurotoxic and associated with increased risk for ALS, Alzheimer’s, brain ischemia, Huntington’s, and Parkinson’s. For those with TPH variants, tryptophan can trigger irritability, e
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Most people think tryptophan leads to serotonin, calmness, or sleepin…
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@biochemistry_nutrition_medlab on Instagram‎: "The 3 major routes of tryptophan after ingestion, metabolism,& absorption in the human gut🧠tryptophan can be absorbed into the blood stream & metabolized via the kynurenine pathway in the liver or via the serotonin or kynirenine pathway in the brain.Within the gut tryptophan can also be funneled towards the kynurenine,indole,or serotonin pathway.These 3 metabolic pathways contain neuroactive metabolites that affect host physiology & neurology.Fadin
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@biochemistry_nutrition_medlab on Instagram‎: "The 3 major routes of …
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