Piezo1 channels play important roles in physiological processes such as tactile sensation, blood pressure (BP) control, cardiac development, inflammatory responses as well as in disease processes.

Vascular calcification, a key risk factor for cardiovascular diseases, is driven by the phenotypic transition of vascular smooth muscle cells from a contractile to an osteogenic phenotype. NEXN, a ...

Researchers have successfully tested a powerful gene therapy, delivered directly into the heart, to reverse heart failure in large animal models. Researchers at the Cardiovascular Research Center at ...

Evidence that 13-M, a unique small molecule disruptor of adrenergic SERCA2 activity reduces infarct size and preserves cardiac function The findings presented suggest that specifically blocking the ...