Anaphase in budding yeast is triggered by cleavage of the central subunit, Scc1, of the chromosomal cohesin complex by the protease separase. Here we show that separase also cleaves the ...

Errors in cell division can cause mutations that lead to cancer, and a new study could shed light on the role of chromosome abnormalities in uncontrolled cell replication. Researchers uncovered the ...

Prognostic significance of circulating tumor cell (CTC) levels at various times during first- and second-line chemotherapy for metastatic breast cancer (MBC). This is an ASCO Meeting Abstract from the ...

In the process of replicating themselves, cells have another choice: do they want to make an identical copy and be left with two cells? Or do they want to make four “half-copies”, in preparation for ...